Listen to events using the Twitch PubSub interface.
yarn add @twurple/auth @twurple/pubsub
or using npm:
npm install @twurple/auth @twurple/pubsub
A good place to start with this library is the documentation which also includes a complete reference of all classes and interfaces, as well as changes and deprecations between major versions.
You can join the Twitch API Libraries Discord Server and ask in #twurple for support.